FUNCTIONS
Saccharomyces Boulardii has been shown to be effective through 50 years of usage and numerous research studies. These studies have demonstrated that Saccharomyces Boulardii:
• Helps to maintain the balance of good microorganisms in the gut.
• Keeps the gut functioning well.
• Promotes intestinal health.
• Protects good microorganisms in the gut.
• Improves consistency of bowel movements.
In a 2010 systematic review and meta-analysis of 31 randomized, placebo-controlled treatment arms in 27 trials (encompassing 5029 adult study patients), S. Boulardii was found to be significantly efficacious and safe in 84% of those treatment arms, and has been used safely in infants and children as well.
Extensively researched and published in European and American peer reviewed journals, S. Boulardii has demonstrated several mechanisms of action. These include (1) secretion of a protease that degrades bacterial toxins, inhibiting them from binding to the intestinal brush border, (2) binding of E coli, Salmonella ssp, and other bacteria, preventing these bacteria from adhering to the intestinal epithelium and, possibly, expelling these pathogens from the body via the stool, (3) stimulation of immune cells of the intestinal mucosa, (4) hindrance of the ability of Candida albicans to form filaments and to adhere and form biofilms, and (5) providing support for an increase in fecal short-chain fatty acids, including butyrate. Putting it plainly, S. Boulardii, stimulates immune response in the intestinal mucosa, enhances the integrity of mucosa and enzymatic activity of the intestinal cells, and neutralizes certain bacterial toxins. Since S. Boulardii is a yeast, it is safe to use during antibiotic therapy
